منابع مشابه
Matrix metalloproteinases and epileptogenesis
Matrix metalloproteinases are vital drivers of synaptic remodeling in health and disease. It is suggested that at early stages of epileptogenesis, inhibition of matrix metalloproteinases may help ameliorate cell death, aberrant network rewiring, and neuroinflammation and prevent development of epilepsy.
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An association between acute CNS infections and seizures is reported in the literature. The etiology of these seizures is, in some cases, precipitated by epileptogenic pathogenesis of the infectious agent in the brain parenchyma. A different etiology of seizures as a consequence of infections, independent of the infectious agent, relates to the inflammatory reaction. Thirdly, the febrile respon...
متن کاملCalcific neurocysticercosis and epileptogenesis.
Neurocysticercosis is responsible for increased rates of seizures and epilepsy in endemic regions. The most common form of the disease, chronic calcific neurocysticercosis, is the end result of the host's inflammatory response to the larval cysticercus of Taenia solium. There is increasing evidence indicating that calcific cysticercosis is not clinically inactive but a cause of seizures or foca...
متن کاملSeizures, Epileptogenesis, and Epilepsy
ber of diverse variables. Some of these factors, such as genes that influence seizure susceptibility, are internal. Others, which alter normal brain excitability, such as traumatic brain injury, are external. As described elsewhere in this volume, these variables can AQ? Specific cross-ref to chapter number? have different and distinct effects. For example, genes may influence both the developm...
متن کاملZinc regulates a key transcriptional pathway for epileptogenesis via metal-regulatory transcription factor 1
Temporal lobe epilepsy (TLE) is the most common focal seizure disorder in adults. In many patients, transient brain insults, including status epilepticus (SE), are followed by a latent period of epileptogenesis, preceding the emergence of clinical seizures. In experimental animals, transcriptional upregulation of CaV3.2 T-type Ca(2+)-channels, resulting in an increased propensity for burst disc...
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ژورنال
عنوان ژورنال: Epilepsy Currents
سال: 2001
ISSN: 1535-7597,1535-7511
DOI: 10.1046/j.1535-7597.2001.00015.x